[HTML][HTML] Canonical Wnt pathway signaling suppresses VCAM-1 expression by marrow stromal and hematopoietic cells
S Malhotra, PW Kincade - Experimental hematology, 2009 - Elsevier
OBJECTIVE: The Wnt family may contribute to hematopoietic stem cell (HSC) maintenance
in bone marrow, but many questions remain concerning mechanisms. Vascular cell
adhesion molecule-1 (VCAM-1) is expressed in cellular compartments of the bone marrow
and might contribute to the HSC niche, but mechanisms concerning its constitutive
expression are largely unknown. We now explore the influence of Wnt signaling on cellular
adhesion molecule expression by bone marrow stromal and hematopoietic cells …
in bone marrow, but many questions remain concerning mechanisms. Vascular cell
adhesion molecule-1 (VCAM-1) is expressed in cellular compartments of the bone marrow
and might contribute to the HSC niche, but mechanisms concerning its constitutive
expression are largely unknown. We now explore the influence of Wnt signaling on cellular
adhesion molecule expression by bone marrow stromal and hematopoietic cells …
